Genetic Testing for Breast Cancer May Benefit Family Members

News
Article

An expert explained that patients with breast cancer who undergo genetic testing may help their family members, regardless of whether patients have children.

Although some patients with breast cancer may not have children, undergoing genetic testing may still be beneficial for other family members, said Dr. Jennifer Plichta, associate professor of surgery and population health sciences at Duke University and director of the breast risk assessment clinic at Duke Cancer Institute.

At the 2024 Miami Breast Cancer Conference, CURE® spoke with Plichta about conversations patients with breast cancer should be having with their health care teams regarding genetic testing.

READ MORE: Field of Cancer Genetics ‘Blossomed’ in Last Decade

Transcript:

Patients should be asking, ‘Is this something I need to consider? Should I be considering genetic testing? Might this have implications not only for my treatment but other cancers I might be at risk for or even for my family members?’

Sometimes you'll have patients that you'll meet that don't have children, great, no problem. But that doesn't always mean that there are other family members — perhaps they have a sibling, and that sibling has children. So maybe it has implications for their brother, their sister, their nieces, their nephews.

Sometimes I have an older patient who's like, ‘Oh, I'm too old, it doesn't matter to me.’ But again, same thing, perhaps it would have implications for their family members. And the most informative person to test is always the person who's had cancer. So if there's someone in the family who's had cancer, those are the ideal people in the family to test. So even if the person in front of you might not do anything with that information, which is totally fine, it's just information. You don't have to act on it. But it could be stuff that their family members could benefit from knowing so that they could consider whether or not they want to undergo genetic testing. And if they do, and it turns out to be positive, what decisions might they want to make that would help impact their future health?

For more news on cancer updates, research and education, don’t forget to subscribe to CURE®’s newsletters here.

Related Videos
For patients with cancer, the ongoing chemotherapy shortage may cause some anxiety as they wonder how they will receive their drugs. However, measuring drugs “down to the minutiae of the milligrams” helped patients receive the drugs they needed, said Alison Tray. Tray is an advanced oncology certified nurse practitioner and current vice president of ambulatory operations at Rutgers Cancer Institute in New Jersey.  If patients are concerned about getting their cancer drugs, Tray noted that having “an open conversation” between patients and providers is key.  “As a provider and a nurse myself, having that conversation, that reassurance and sharing the information is a two-way conversation,” she said. “So just knowing that we're taking care of you, we're going to make sure that you receive the care that you need is the key takeaway.” In June 2023, many patients were unable to receive certain chemotherapy drugs, such as carboplatin and cisplatin because of an ongoing shortage. By October 2023, experts saw an improvement, although the “ongoing crisis” remained.  READ MORE: Patients With Lung Cancer Face Unmet Needs During Drug Shortages “We’re really proud of the work that we could do and achieve that through a critical drug shortage,” Tray said. “None of our patients missed a dose of chemotherapy and we were able to provide that for them.” Tray sat down with CURE® during the 49th Annual Oncology Nursing Society Annual Congress to discuss the ongoing chemo shortage and how patients and care teams approached these challenges. Transcript: Particularly at Hartford HealthCare, when we established this infrastructure, our goal was to make sure that every patient would get the treatment that they need and require, utilizing the data that we have from ASCO guidelines to ensure that we're getting the optimal high-quality standard of care in a timely fashion that we didn't have to delay therapies. So, we were able to do that by going down to the minutiae of the milligrams on hand, particularly when we had a lot of critical drug shortages. So it was really creating that process to really ensure that every patient would get the treatment that they needed. For more news on cancer updates, research and education, don’t forget to subscribe to CURE®’s newsletters here.
Image of a woman with black hair.
Image of a woman with brown shoulder-length hair in front of a gray background that says CURE.
Woman with dark brown hair and pink lipstick wearing a light pink blouse with a light brown blazer. Patients should have conversations with their providers about treatments after receiving diagnoses.
Man in a navy suit with a purple tie. Dr. Saby George talks to CURE about how treatment with Opdivo could mitigate disparities in patients with kidney cancer.
Dr. Andrea Apolo in an interview with CURE
Dr. Kim in an interview with CURE
Dr. Nguyen, from Stanford Health, in an interview with CURE